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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Carcinoma, Non-Small-Cell Lung
Clinicaltrials.gov:
EU CTIS:
#2025-520730-28-00
Other:
#61186372NSC2012
Trials at a glance
Status
Enrolling
Condition
Carcinoma, Non-Small-Cell Lung
Trial type
Interventional
Trial phase
Phase 2
Investigational
product
product
Amivantamab
Chemotherapy: Carboplatin
Chemotherapy: Pemetrexed
Lazertinib
Age
18+ years old
Biological sex
All
Placebo?
No
Trial start date
December 16, 2024
Trial end date
December 26, 2030
CT.gov ID
#NCT06667076
Share the trial ID with your doctor to see if trial participation is right for you. Participation depends on an independent medical assessment.
Countries:
- Puerto Rico,
- United States
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Enrolling
Ames 4846834, Iowa 4862182, United States, 50010
Enrolling
Orlando 4167147, Florida 4155751, United States, 32803
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San Juan 4568127, Puerto Rico, 00918
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Sioux Falls 5231851, South Dakota 5769223, United States, 57105
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Memphis 4641239, Tennessee 4662168, United States, 38120
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Miami 4164138, Florida 4155751, United States, 33176
Enrolling
Boca Raton 4148411, Florida 4155751, United States, 33486
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Jacksonville 4160021, Florida 4155751, United States, 32207
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Boston 4930956, Massachusetts 6254926, United States, 02215
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Boston 4930956, Massachusetts 6254926, United States, 02118
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San Francisco 5391959, California 5332921, United States, 94115
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Decatur 4236895, Illinois 4896861, United States, 62526
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Los Alamitos 5368304, California 5332921, United States, 90720
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Los Angeles 5368361, California 5332921, United States, 90048
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Newark 4143861, Delaware 4142224, United States, 19713
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Duarte 5344147, California 5332921, United States, 91010
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Lancaster 5364940, California 5332921, United States, 93534
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Newnan 4212684, Georgia 4197000, United States, 30265
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Zion 4917358, Illinois 4896861, United States, 60099
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Corona 5339631, California 5332921, United States, 92882
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Long Beach 5367929, California 5332921, United States, 90813
Enrolling
Irvine 5359777, California 5332921, United States, 92618
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Goodyear 5296266, Arizona 5551752, United States, 85338
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Huntington Beach 5358705, California 5332921, United States, 92648
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South Pasadena 5397717, California 5332921, United States, 91030
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Upland 5404915, California 5332921, United States, 91786
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Huntsville 4068590, Alabama 4829764, United States, 35805
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Westbury 5144040, New York 5128638, United States, 11590
Enrolling
Kingwood 7534469, Texas 4736286, United States, 77339
Enrolling
Boston 4930956, Massachusetts 6254926, United States, 02215
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Lebanon 5088597, New Hampshire 5090174, United States, 03756
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Schenectady 5136454, New York 5128638, United States, 12308
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Fort Myers 4155995, Florida 4155751, United States, 33916
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St. Petersburg 4171563, Florida 4155751, United States, 33705
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West Palm Beach 4177887, Florida 4155751, United States, 33401
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Fort Wayne 4920423, Indiana 4921868, United States, 46804
Enrolling
Glendale 5352423, California 5332921, United States, 91206
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Atlanta 4180439, Georgia 4197000, United States, 30303
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East Syracuse 5116079, New York 5128638, United States, 13057
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New York 5128581, New York 5128638, United States, 10032
Enrolling
Teaneck 5105262, New Jersey 5101760, United States, 07666
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Hinsdale 4896012, Illinois 4896861, United States, 60521
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Flemington 5098124, New Jersey 5101760, United States, 08822
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Salt Lake City 5780993, Utah 5549030, United States, 84112
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Niles 4903730, Illinois 4896861, United States, 60714
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Noblesville 4924198, Indiana 4921868, United States, 46062
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Fort Worth 4691930, Texas 4736286, United States, 76104
Enrolling
Jackson 4431410, Mississippi 4436296, United States, 39202
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Walnut Creek 5406990, California 5332921, United States, 94598
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Vallejo 5405380, California 5332921, United States, 94589
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Oakland 5378538, California 5332921, United States, 94611
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Roseville 5388881, California 5332921, United States, 95661
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San Francisco 5391959, California 5332921, United States, 94115
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Santa Clara 5393015, California 5332921, United States, 95051
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Walnut Creek 5406990, California 5332921, United States, 94596
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Wynnewood 5220230, Pennsylvania 6254927, United States, 19096
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Bryn Mawr 5182063, Pennsylvania 6254927, United States, 19010
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Paoli 5205037, Pennsylvania 6254927, United States, 19301
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Mineola 5127134, New York 5128638, United States, 11501
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Glendale 5352423, California 5332921, United States, 91204
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Golden 5423294, Colorado 5417618, United States, 80401
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Houston 4699066, Texas 4736286, United States, 77030
Enrolling
Greenbrae 5354013, California 5332921, United States, 94904
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Silver Spring 4369596, Maryland 4361885, United States, 20904
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West Reading 5218867, Pennsylvania 6254927, United States, 19611
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Washington D.C. 4140963, District of Columbia 4138106, United States, 20007
Enrolling
Tampa 4174757, Florida 4155751, United States, 33612
Enrolling
The Bronx 5110266, New York 5128638, United States, 10461
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Morristown 5101427, New Jersey 5101760, United States, 07960
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New York 5128581, New York 5128638, United States, 10016
Enrolling
Denver 5419384, Colorado 5417618, United States, 80206
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Shirley 5138022, New York 5128638, United States, 11967
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Vancouver 5814616, Washington 5815135, United States, 98684
Enrolling
Eugene 5725846, Oregon 5744337, United States, 97401
Enrolling
Houston 4699066, Texas 4736286, United States, 77030
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Springfield 4409896, Missouri 4398678, United States, 65807
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Glendale 5352423, California 5332921, United States, 91203
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Portland 5746545, Oregon 5744337, United States, 97239
Enrolling
Orlando 4167147, Florida 4155751, United States, 32806
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Summit 5105127, New Jersey 5101760, United States, 07901
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Philadelphia 4560349, Pennsylvania 6254927, United States, 19104
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Atlanta 4180439, Georgia 4197000, United States, 30318
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Atlanta 4180439, Georgia 4197000, United States, 30309
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Santa Rosa 5393287, California 5332921, United States, 95403
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Fullerton 5351247, California 5332921, United States, 92835
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Wilson 4499389, North Carolina 4482348, United States, 27893
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El Paso 5520993, Texas 4736286, United States, 79915
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The Woodlands 4736476, Texas 4736286, United States, 77380
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Lone Tree 5429208, Colorado 5417618, United States, 80124
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New Brunswick 5101717, New Jersey 5101760, United States, 08901
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Nashville 4644585, Tennessee 4662168, United States, 37203
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Denver 5419384, Colorado 5417618, United States, 80218
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Santa Barbara 5392952, California 5332921, United States, 93105
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Daphne 4058219, Alabama 4829764, United States, 36526
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Orange 5379513, California 5332921, United States, 92868
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Spokane 5811696, Washington 5815135, United States, 99208
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Palo Alto 5380748, California 5332921, United States, 94301
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Sacramento 5389489, California 5332921, United States, 95816
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Knoxville 4634946, Tennessee 4662168, United States, 37909
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Chattanooga 4612862, Tennessee 4662168, United States, 37404
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Nashville 4644585, Tennessee 4662168, United States, 37203
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Dallas 4684888, Texas 4736286, United States, 75246
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Odessa 5527554, Texas 4736286, United States, 79761
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Webster 4740423, Texas 4736286, United States, 77598
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Fort Lauderdale 4155966, Florida 4155751, United States, 33316
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Glendale 5352423, California 5332921, United States, 90015
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Tyler 4738214, Texas 4736286, United States, 75701
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Philadelphia 4560349, Pennsylvania 6254927, United States, 19107
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Ypsilanti 5015688, Michigan 5001836, United States, 48197
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Kansas City 4393217, Missouri 4398678, United States, 64108
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Sacramento 5389489, California 5332921, United States, 95630
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San Francisco 5391959, California 5332921, United States, 94143
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Los Angeles 5368361, California 5332921, United States, 90033
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Dallas 4684888, Texas 4736286, United States, 75390
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Gainesville 4156404, Florida 4155751, United States, 32608
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Athens 4180386, Georgia 4197000, United States, 30607
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Minneapolis 5037649, Minnesota 5037779, United States, 55455
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Orange 5379513, California 5332921, United States, 92868
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La Jolla 5363943, California 5332921, United States, 92093
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Cincinnati 4508722, Ohio 5165418, United States, 45219
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Chicago 4887398, Illinois 4896861, United States, 60612
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Fairway 4271358, Kansas 4273857, United States, 66205
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Baltimore 4347778, Maryland 4361885, United States, 21201
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Albuquerque 5454711, New Mexico 5481136, United States, 87102
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Knoxville 4634946, Tennessee 4662168, United States, 37920
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Los Angeles 5368361, California 5332921, United States, 90067
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Murrieta 5375911, California 5332921, United States, 92562
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Fairfax 4758023, Virginia 6254928, United States, 22031
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Olympia 5805687, Washington 5815135, United States, 98506
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Washington D.C. 4140963, District of Columbia 4138106, United States, 20422
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St Louis 4407066, Missouri 4398678, United States, 63110
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Atlanta 4180439, Georgia 4197000, United States, 30322
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New Haven 4839366, Connecticut 4831725, United States, 06520
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