A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

Inclusion:

* Documented diagnosis of multiple myeloma (MM) as defined by the criteria below:

1. MM diagnosis according to the international myeloma working group (IMWG) diagnostic criteria

2. Measurable disease at screening as assessed by central laboratory

* Received at least 3 prior lines of antimyeloma therapy including a proteasome inhibitor (PI), an immunomodulatory drug (IMiD), and an anti-cluster of differentiation (CD) 38 monoclonal antibody (mAb)

* Documented evidence of progressive disease(PD) or failure to achieve a response to the last line of therapy based on investigator's determination of response by the IMWG criteria

* Have discontinued concurrent use of any other anticancer treatment (including nonpalliative radiotherapy) or investigational agent

* Have an eastern cooperative oncology group (ECOG) performance status (PS) of 0 to 2 at screening and immediately before the start of study treatment administration

Exclusion:

* Suspected or known allergies, hypersensitivity, or intolerance to excipients of JNJ-79635322

* Had major surgery within 2 weeks before first dose or has planned major surgery during study treatment phase

* Known active or prior central nervous system (CNS) involvement or exhibits clinical signs of meningeal involvement of MM

* Participant has leptomeningeal disease

* Participant has a prior or concurrent second malignancy the natural history or treatment of which could likely interfere with any study endpoints of safety or the efficacy of the study treatment