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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Carcinoma, Non-Small-Cell Lung
Clinicaltrials.gov:
EU CTIS:
#2025-520730-28-00
Other:
#61186372NSC2012
Trials at a glance
Status
Enrolling
Condition
Carcinoma, Non-Small-Cell Lung
Trial type
Interventional
Trial phase
Phase 2
Investigational
product
product
Amivantamab
Chemotherapy: Carboplatin
Chemotherapy: Pemetrexed
Lazertinib
Age
18+ years old
Biological sex
All
Placebo?
No
Trial start date
December 16, 2024
Trial end date
December 26, 2030
CT.gov ID
#NCT06667076
Share the trial ID with your doctor to see if trial participation is right for you. Participation depends on an independent medical assessment.
Countries:
- Belgium,
- Finland,
- France,
- Germany,
- Greece,
- Israel,
- Italy,
- Poland,
- Portugal,
- Puerto Rico,
- Spain,
- United Kingdom,
- United States
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Enrolling
Ames, Iowa, United States, 50010
Enrolling
Orlando, Florida, United States, 32803
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Thessaloniki, Greece, 546 39
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Marseille, France, 13005
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Thessaloniki, Greece, 54639
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Charlotte, North Carolina, United States, 28204
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Winston-Salem, North Carolina, United States, 27157
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San Juan, Puerto Rico, 00918
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Miami, Florida, United States, 33176
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Boca Raton, Florida, United States, 33486
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Jacksonville, Florida, United States, 32207
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Boston, Massachusetts, United States, 02215
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Boston, Massachusetts, United States, 02118
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Yvoir, Belgium, 5530
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Brest, France, 29200
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La Tronche, France, 38700
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San Francisco, California, United States, 94115
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Decatur, Illinois, United States, 62526
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Los Alamitos, California, United States, 90720
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Los Angeles, California, United States, 90048
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Bydgoszcz, Poland, 85 796
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Newark, Delaware, United States, 19713
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Cincinnati, Ohio, United States, 45220
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Duarte, California, United States, 91010
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Lancaster, California, United States, 93534
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Newnan, Georgia, United States, 30265
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Zion, Illinois, United States, 60099
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Corona, California, United States, 92882
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Long Beach, California, United States, 90813
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Irvine, California, United States, 92618
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Goodyear, Arizona, United States, 85338
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Huntington Beach, California, United States, 92648
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South Pasadena, California, United States, 91030
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Upland, California, United States, 91786
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Huntsville, Alabama, United States, 35805
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Kingwood, Texas, United States, 77339
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Boston, Massachusetts, United States, 02215
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Lebanon, New Hampshire, United States, 03756
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Durham, North Carolina, United States, 27710
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Schenectady, New York, United States, 12308
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Fort Myers, Florida, United States, 33916
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West Palm Beach, Florida, United States, 33401
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St. Petersburg, Florida, United States, 33701
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Roma, Italy, 00168
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Fort Wayne, Indiana, United States, 46804
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Ghent, Belgium, 9000
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Glendale, California, United States, 91206
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Atlanta, Georgia, United States, 30303
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Greater London, United Kingdom, SE1 9RT
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Helsinki, Finland, 00290
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East Syracuse, New York, United States, 13057
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Athens, Greece, 115 26
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New York, New York, United States, 10032
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Teaneck, New Jersey, United States, 07666
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Barcelona, Spain, 08035
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Santiago de Compostela, Spain, 15706
Enrolling
Lisbon, Portugal, 1350-352
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Madrid, Spain, 28041
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Valencia, Spain, 46026
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Jerez de la Frontera, Spain, 11407
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Salt Lake City, Utah, United States, 84112
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Saint-Herblain, France, 44805
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Niles, Illinois, United States, 60714
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Peoria, Illinois, United States, 61615
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Noblesville, Indiana, United States, 46062
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Porto, Portugal, 4200 072
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Rozzano, Italy, 20089
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Fort Worth, Texas, United States, 76104
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Jackson, Mississippi, United States, 39202
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Philadelphia, Pennsylvania, United States, 19114
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Walnut Creek, California, United States, 94598
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Vallejo, California, United States, 94589
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Oakland, California, United States, 94611
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Roseville, California, United States, 95661
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San Francisco, California, United States, 94115
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Santa Clara, California, United States, 95051
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Walnut Creek, California, United States, 94596
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München, Germany, 80336
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Wynnewood, Pennsylvania, United States, 19096
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Bryn Mawr, Pennsylvania, United States, 19010
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Paoli, Pennsylvania, United States, 19301
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Mineola, New York, United States, 11501
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Glendale, California, United States, 91204
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Golden, Colorado, United States, 80401
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Houston, Texas, United States, 77030
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Greenbrae, California, United States, 94904
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Silver Spring, Maryland, United States, 20904
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Jacksonville, Florida, United States, 32224
Enrolling
Rochester, Minnesota, United States, 55905
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West Reading, Pennsylvania, United States, 19611
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Washington D.C., District of Columbia, United States, 20007
Enrolling
Charleston, South Carolina, United States, 29425
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Kfar Saba, Israel, 44281
Enrolling
Piraeus, Greece, 18537
Enrolling
Tampa, Florida, United States, 33612
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The Bronx, New York, United States, 10461
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Morristown, New Jersey, United States, 07960
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New York, New York, United States, 10016
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Warsaw, Poland, 02-781
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Denver, Colorado, United States, 80206
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Shirley, New York, United States, 11967
Enrolling
Vancouver, Washington, United States, 98684
Enrolling
Eugene, Oregon, United States, 97401
Enrolling
Houston, Texas, United States, 77030
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Springfield, Missouri, United States, 65807
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Portland, Oregon, United States, 97239
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Orlando, Florida, United States, 32806
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Ravenna, Italy, 48121
Enrolling
Oulu, Finland, 90220
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Summit, New Jersey, United States, 07901
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Dallas, Texas, United States, 75235
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Philadelphia, Pennsylvania, United States, 19104
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Atlanta, Georgia, United States, 30318
Enrolling
Atlanta, Georgia, United States, 30309
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Fullerton, California, United States, 92835
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Santa Rosa, California, United States, 95403
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Haifa, Israel, 3109601
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Wilson, North Carolina, United States, 27893
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El Paso, Texas, United States, 79915
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The Woodlands, Texas, United States, 77380
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Lone Tree, Colorado, United States, 80124
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Sutton, United Kingdom, SM2 5PT
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London, United Kingdom, SW3 6JJ
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Chicago, Illinois, United States, 60607
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New Brunswick, New Jersey, United States, 08901
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Nashville, Tennessee, United States, 37203
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Denver, Colorado, United States, 80218
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Santa Barbara, California, United States, 93105
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Ramat Gan, Israel, 5262000
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Beersheba, Israel, 8457108
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Daphne, Alabama, United States, 36526
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Leipzig, Germany, 04277
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Orange, California, United States, 92868
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Spokane, Washington, United States, 99208
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Palo Alto, California, United States, 94301
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Sacramento, California, United States, 95816
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Miami, Florida, United States, 33136
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Knoxville, Tennessee, United States, 37909
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Nashville, Tennessee, United States, 37203
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Chattanooga, Tennessee, United States, 37404
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Tyler, Texas, United States, 75702
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Dallas, Texas, United States, 75246
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San Antonio, Texas, United States, 78217
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Austin, Texas, United States, 78745
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Webster, Texas, United States, 77598
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Manchester, United Kingdom, M20 4BX
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Liverpool, United Kingdom, L78YA
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Cerritos, California, United States, 90703
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Fort Lauderdale, Florida, United States, 33316
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Tyler, Texas, United States, 75701
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Philadelphia, Pennsylvania, United States, 19107
Enrolling
Athens, Greece, 11527
Enrolling
Torquay, United Kingdom, TQ2 7AA
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Ypsilanti, Michigan, United States, 48197
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Kansas City, Missouri, United States, 64108
Enrolling
Turku, Finland, 20521
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Sacramento, California, United States, 95630
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San Francisco, California, United States, 94143
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Los Angeles, California, United States, 90033
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Dallas, Texas, United States, 75390
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Guimarães, Portugal, 4835 044
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Braga, Portugal, 4710 243
Enrolling
Vila Nova de Gaia, Portugal, 4434 502
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Loures, Portugal, 2674 514
Enrolling
Gainesville, Florida, United States, 32610
Enrolling
Leuven, Belgium, 3000
Enrolling
Athens, Georgia, United States, 30607
Enrolling
Minneapolis, Minnesota, United States, 55455
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Orange, California, United States, 92868
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La Jolla, California, United States, 92093
Enrolling
Cincinnati, Ohio, United States, 45219
Enrolling
Chicago, Illinois, United States, 60612
Enrolling
Fairway, Kansas, United States, 66205
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Baltimore, Maryland, United States, 21201
Enrolling
Ann Arbor, Michigan, United States, 48105
Enrolling
Albuquerque, New Mexico, United States, 87102
Enrolling
Knoxville, Tennessee, United States, 37920
Enrolling
Gdansk, Poland, 80 952
Enrolling
Los Angeles, California, United States, 90067
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Murrieta, California, United States, 92562
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Fairfax, Virginia, United States, 22031
Enrolling
Olympia, Washington, United States, 98506
Enrolling
Olsztyn, Poland, 10-357
Enrolling
Washington D.C., District of Columbia, United States, 20422
Enrolling
St Louis, Missouri, United States, 63110
Enrolling
Atlanta, Georgia, United States, 30322
Enrolling
New Haven, Connecticut, United States, 06520
Enrolling
Genk, Belgium, 3600
Completed
Sioux Falls, South Dakota, United States, 57105
Completed
Memphis, Tennessee, United States, 38120
Completed
Westbury, New York, United States, 11590
Completed
Hinsdale, Illinois, United States, 60521
Completed
Flemington, New Jersey, United States, 08822
Completed
Glendale, California, United States, 91203
Completed
Odessa, Texas, United States, 79761
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More than 50 sites in this region
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More than 10 sites in this region
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Less than 10 sites in this region
Individual sites
Access detailed information on the trial:
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