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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Colorectal Neoplasms
Clinicaltrials.gov:
EU CTIS:
#2024-513852-13-00
Other:
#61186372COR3001
Trials at a glance
Status
Enrolling
Condition
Colorectal Neoplasms
Trial type
Interventional
Trial phase
Phase 3
Investigational
product
product
5-fluorouracil
Amivantamab
Cetuximab
Irinotecan Hydrochloride
Leucovorin calcium/Levoleucovorin
Oxaliplatin
Age
18+ years old
Biological sex
All
Placebo?
No
Trial start date
October 18, 2024
Trial end date
January 30, 2032
CT.gov ID
#NCT06662786
Share the trial ID with your doctor to see if trial participation is right for you. Participation depends on an independent medical assessment.
Countries:
- Belgium,
- Brazil,
- Canada,
- China,
- France,
- Germany,
- Hungary,
- India,
- Israel,
- Italy,
- Japan,
- Malaysia,
- Netherlands,
- Poland,
- Puerto Rico,
- South Korea,
- Spain,
- Sweden,
- Taiwan,
- Turkey (Türkiye),
- United Kingdom,
- United States
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Enrolling
Ghent, Belgium, 9000
Enrolling
Adana, Turkey (Türkiye), 01060
Enrolling
Cambridge, United Kingdom, CB2 0QQ
Enrolling
Orlando, Florida, United States, 32804
Enrolling
Nagoya, Japan, 464 8681
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Ankara, Turkey (Türkiye), 06800
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Amsterdam, Netherlands, 1066 CX
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Calgary, Alberta, Canada, T2N 5G2
Enrolling
Seoul, South Korea, 05505
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Hamburg, Germany, 22763
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Vitória, Brazil, 29043 260
Enrolling
Tel Aviv, Israel, 69710
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East Brunswick, New Jersey, United States, 08816
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Kortrijk, Belgium, 8500
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Pisa, Italy, 56126
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Kolkata, India, 700053
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Istanbul, Turkey (Türkiye), 34147
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Gilbert, Arizona, United States, 85234
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Temple, Texas, United States, 76508
Enrolling
Beijing, China, 100142
Enrolling
Beijing, China, 100050
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Bialystok, Poland, 15 027
Enrolling
Birmingham, United Kingdom, B9 5ST
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Bakersfield, California, United States, 93309
Enrolling
Poitiers, France, 86000
Enrolling
Nantes, France, 44000
Enrolling
Los Alamitos, California, United States, 90720
Enrolling
Hull, United Kingdom, HU16 5JQ
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Liège, Belgium, 4000
Enrolling
Montreal, Quebec, Canada, H2X 0C1
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Warsaw, Poland, 02 781
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Berlin, Germany, 13353
Enrolling
Chiba, Japan, 260 0801
Enrolling
Cleveland, Ohio, United States, 44111
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Mayfield Heights, Ohio, United States, 44124
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Independence, Ohio, United States, 44131
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Mansfield, Ohio, United States, 44906
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Warrensville Heights, Ohio, United States, 44122
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Strongsville, Ohio, United States, 44136
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Sandusky, Ohio, United States, 44870
Enrolling
Pamplona, Spain, 31008
Enrolling
Santa Maria, Brazil, 97015 450
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Las Vegas, Nevada, United States, 89169
Enrolling
Pune, India, 411004
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Ankara, Turkey (Türkiye), 06200
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Tilburg, Netherlands, 5022 GC
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Rotterdam, Netherlands, 3015 GD
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Essen, Germany, 45147
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Taiyuan, China, 030001
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West Palm Beach, Florida, United States, 33401-3406
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St. Petersburg, Florida, United States, 33701-4553
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Fort Myers, Florida, United States, 33901
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Fort Wayne, Indiana, United States, 46804
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Philadelphia, Pennsylvania, United States, 19111
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Seattle, Washington, United States, 98109
Enrolling
Shanghai, China, 200032
Enrolling
São Paulo, Brazil, 01509 900
Enrolling
Jaú, Brazil, 17210 080
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São José do Rio Preto, Brazil, 15090 000
Enrolling
São Paulo, Brazil, 01246 000
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Barretos, Brazil, 14780 070
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Caxias do Sul, Brazil, 95070 560
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Canton, Ohio, United States, 44718
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Ankara, Turkey (Türkiye), 06560
Enrolling
Washington D.C., District of Columbia, United States, 20007
Enrolling
Atlanta, Georgia, United States, 30303
Enrolling
Guangzhou, China, 519041
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Ankara, Turkey (Türkiye), 06010
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Villejuif, France, 94805
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Jerusalem, Israel, 9112001
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Harbin, China, 150081
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Hattiesburg, Mississippi, United States, 39401
Enrolling
Detroit, Michigan, United States, 48202
Enrolling
New York, New York, United States, 10032
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Springdale, Arkansas, United States, 72762
Enrolling
Lille, France, 59000
Enrolling
Pessac, France, 33604
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Lyon, France, 69008
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Paris, France, 75571
Enrolling
Haine Saint Paul La Louviere, Belgium, 7100
Enrolling
Barcelona, Spain, 08035
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Valencia, Spain, 46010
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Madrid, Spain, 28007
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Madrid, Spain, 28041
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Madrid, Spain, 28034
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Seville, Spain, 41013
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Barcelona, Spain, 08025
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Cheras, Malaysia, 56000
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Kuala Lumpur, Malaysia, 50586
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Porto Alegre, Brazil, 91350 200
Enrolling
George Town, Malaysia, 10450
Enrolling
Ipoh, Malaysia, 30450
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Salvador, Brazil, 40050 410
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Kuching, Malaysia, 93586
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Wuhan, China, 430079
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Huizhou, China, 516001
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Changsha, China, 410013
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Peoria, Illinois, United States, 61615
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Fairfax, Virginia, United States, 22031
Enrolling
Anderlecht, Belgium, 1070
Enrolling
Avignon, France, 84918
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Montpellier, France, 34298
Enrolling
Lodz, Poland, 93 339
Enrolling
Rozzano, Italy, 20089
Enrolling
Milan, Italy, 20133
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Padua, Italy, 35128
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Meldola, Italy, 47014
Enrolling
Kaohsiung City, Taiwan, 83301
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Kaohsiung City, Taiwan, 80756
Enrolling
Stockholm, Sweden, 171 76
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Munich, Germany, 81377
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Frankfurt am Main, Germany, 60488
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Daegu, South Korea, 41404
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Shenyang, China, 110042
Enrolling
Taoyuan District, Taiwan, 333
Enrolling
Glendale, California, United States, 91204
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Houston, Texas, United States, 77030
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Varanasi, India, 221005
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Eger, Hungary, 3300
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Istanbul, Turkey (Türkiye), 34899
Enrolling
Amersfoort, Netherlands, 3813 TZ
Enrolling
Baltimore, Maryland, United States, 21237
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The Bronx, New York, United States, 10461
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New York, New York, United States, 10003
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New York, New York, United States, 10009
Enrolling
Northwood, United Kingdom, HA6 2RN
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New York, New York, United States, 10016
Enrolling
Gliwice, Poland, 44 100
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Chūōku, Japan, 104 0045
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Kashiwa, Japan, 277 8577
Enrolling
Putrajaya, Malaysia, 62250
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Heidelberg, Germany, 69120
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Tainan, Taiwan, 704
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Osaka, Japan, 540 0006
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Taipei, Taiwan, 10043
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Omaha, Nebraska, United States, 68130
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Konya, Turkey (Türkiye), 42090
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Shirley, New York, United States, 11967
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New Orleans, Louisiana, United States, 70121
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Portland, Oregon, United States, 97239
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Osaka, Japan, 541 8567
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Ottawa, Ontario, Canada, K1H 8L6
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Barrio Monacillos, Puerto Rico, 00935
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Beijing, China, 100034
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Shenzhen, China, 518036
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Beijing, China, 100191
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Mineola, New York, United States, 11501
Enrolling
Freiburg im Breisgau, Germany, 79110
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Toronto, Ontario, Canada, M5G1X6
Enrolling
Santa Rosa, California, United States, 95403
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Petah Tikva, Israel, 4941492
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Nijmegen, Netherlands, 6525 GA
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Delhi, India, 110085
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Haifa, Israel, 3109601
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Richmond, Virginia, United States, 23249
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Denver, Colorado, United States, 80218
Enrolling
Sutton, United Kingdom, SM2 5PT
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New Brunswick, New Jersey, United States, 08901
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Nashville, Tennessee, United States, 37203
Enrolling
Olsztyn, Poland, 10 228
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Opole, Poland, 45 061
Enrolling
Gothenburg, Sweden, 413 45
Enrolling
Sakarya, Turkey (Türkiye), 54290
Enrolling
Seoul, South Korea, 06351
Enrolling
Budapest, Hungary, 1082
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Seoul, South Korea, 03080
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Seoul, South Korea, 03722
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Ramat Gan, Israel, 52621
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Shizuoka, Japan, 411 8777
Enrolling
Lund, Sweden, 222 42
Enrolling
São Paulo, Brazil, 05651 900
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Stockholm, Sweden, 118 83
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London, United Kingdom, EC1A 7BE
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Leeds, United Kingdom, LS9 7TF
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Jonesboro, Arkansas, United States, 72401
Enrolling
Grand Rapids, Michigan, United States, 49503
Enrolling
Guangzhou, China, 510062
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Seattle, Washington, United States, 98104
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Edmonds, Washington, United States, 98026
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Issaquah, Washington, United States, 98029
Enrolling
Szeged, Hungary, 6720
Enrolling
Brzozów, Poland, 36 200
Enrolling
Mumbai, India, 400012
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Cleveland, Ohio, United States, 44195
Enrolling
Tel Aviv, Israel, 6423906
Enrolling
San Antonio, Texas, United States, 78240
Enrolling
Dallas, Texas, United States, 75246
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Abilene, Texas, United States, 79606
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Tokyo, Japan, 135 8550
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Seoul, South Korea, 06591
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Hangzhou, China, 310003
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Nanchang, China, 330006
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Changchun, China, 130021
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Hangzhou, China, 310009
Enrolling
Guangzhou, China, 510655
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Suita, Japan, 565 0871
Enrolling
Philadelphia, Pennsylvania, United States, 19107
Enrolling
Tianjin, China, 300060
Enrolling
Torrance, California, United States, 90505
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Santa Monica, California, United States, 90404
Enrolling
Utrecht, Netherlands, 3584 CX
Enrolling
Los Angeles, California, United States, 90033
Enrolling
Dallas, Texas, United States, 75390
Enrolling
Dresden, Germany, 01307
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Edegem, Belgium, 2650
Enrolling
Leuven, Belgium, 3000
Enrolling
Ulm, Germany, 89081
Enrolling
Mainz, Germany, 55131
Enrolling
London, United Kingdom, NW1 2BU
Enrolling
Cleveland, Ohio, United States, 44106
Enrolling
Kuala Lumpur, Malaysia, 59100
Enrolling
Pittsburgh, Pennsylvania, United States, 15232 1301
Enrolling
Ann Arbor, Michigan, United States, 48109
Enrolling
Albuquerque, New Mexico, United States, 87102
Enrolling
Chapel Hill, North Carolina, United States, 27599
Enrolling
Gdansk, Poland, 80 214
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Uppsala, Sweden, SE 751 85
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Ann Arbor, Michigan, United States, 48105
Enrolling
Richmond, Virginia, United States, 23298
Enrolling
Arlington, Virginia, United States, 22201
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St Louis, Missouri, United States, 63110
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Sichuan, China, 610044
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Edinburgh, United Kingdom, EH4 2XU
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Madison, Wisconsin, United States, 53705
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Atlanta, Georgia, United States, 30322
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Biała Podlaska, Poland, 21 500
Enrolling
Wooster, Ohio, United States, 44691
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New Haven, Connecticut, United States, 06519
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Beer Yaakov, Israel, 70300
Enrolling
Hangzhou, China, 310022
Completed
Pécs, Hungary, 7624
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More than 50 sites in this region
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More than 10 sites in this region
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Less than 10 sites in this region
Individual sites
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